Ro 67-7476, CAS [[298690-60-5]]

Product Overview

• Article Name: Ro 67-7476, CAS [[298690-60-5]]
• Biozol Catalog Number: BYT-ORB1304163
• Supplier Catalog Number: orb1304163
• Alternative Catalog Number: BYT-ORB1304163-1,BYT-ORB1304163-2,BYT-ORB1304163-5,BYT-ORB1304163-10,BYT-ORB1304163-25,BYT-ORB1304163-50,BYT-ORB1304163-100
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: cAMP accumulation, Inhibitor, excitatory postsynaptic potentials, Metabotropic glutamate receptors, mGluR, mGluR1, neuronal culture, inhibit, traumatic injury, Ro 67 7476, Ro 677476, Ro 67-7476

Product Description

Ro 67-7476 is a potent and selective positive allosteric modulator of rat mGluR1a (EC50 = 60.1 nM), enhancing glutamate-induced calcium release. It also acts as a P-ERK1/2 agonist, independently stimulating ERK1/2 phosphorylation (EC50 = 163.3 nM). This compound is a valuable research tool for studying mGluR1 signaling in neurological disease models, both in vitro and in vivo.

Product Properties

• Molecular Weight: 319.39
• Purity: 99.69% (May vary between batches)
• CAS Number: [298690-60-5]
• Formula: C17H18FNO2S
• Target: GluR

Application Notes

• Application Notes: Solubility: DMSO:50 mg/mL (156.55 mM)