Cynomolgus IL-23 R Protein, Unconjugated Preis auf Anfrage

Product Overview

• Article Name: Cynomolgus IL-23 R Protein, Unconjugated Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB1496206
• Supplier Catalog Number: orb1496206
• Alternative Catalog Number: BYT-ORB1496206-1,BYT-ORB1496206-100
• Manufacturer: Biorbyt
• Category: Proteine/Peptide
• Species Reactivity: Monkey
• Conjugation: Unconjugated
• Alternative Names: IL-23 R,IL-23 Receptor

Product Description

Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.

Product Properties

• Molecular Weight: 64.5 kDa
• NCBI: 7
• UniProt: G7NWY5
• Buffer: PBS, pH7.4
• Purity: 95%
• Form: Liquid
• Target: IL-23 R

Application Notes

• Application Notes: Application Notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.5 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation

Images

Immobilized Biotinylated Human IL-23A & IL-12B Heterodimer Protein, His, Avitag & Tag Free at 1 µg/mL (100 µL/well) on streptavidin (Cat. No. orb668907) precoated (0.5 µg/well) plate can bind Cynomolgus IL-23 R, Fc Tag (Cat. No. orb1496206) with a linear range of 0.1-3 ng/mL (QC tested).