LSKL TFA, CAS [[2828433-17-4]]

Product Overview

• Article Name: LSKL TFA, CAS [[2828433-17-4]]
• Biozol Catalog Number: BYT-ORB1679211
• Supplier Catalog Number: orb1679211
• Alternative Catalog Number: BYT-ORB1679211-1, BYT-ORB1679211-10, BYT-ORB1679211-100, BYT-ORB1679211-25, BYT-ORB1679211-5, BYT-ORB1679211-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: LSKL, Inhibitor of Thrombospondin (TSP 1) (TFA), LSKL, Inhibitor of Thrombospondin (TSP-1), LSKL, Inhibitor of Thrombospondin (TSP1) (TFA), LSKL, Inhibitor of Thrombospondin (TSP-1) (TFA), H-Leu-Ser-Lys-Leu-NH2 TFA, H-Leu-Ser-Lys-Leu-NH2 TFA(283609-79-0 TFA), TGF-beta1, TGF-beta/Smad, TGF-beta Receptor, TGFbeta, TGFbeta/Smad, TGF-b/Smad, TGFb, TGFbeta, TGF-beta, Smad

Product Description

LSKL TFA is a blood-brain barrier permeable TGF-beta1 antagonist derived from LAP. It functions by inhibiting the TSP-1/LAP interaction, thereby blocking TGF-beta1 activation. This mechanism has demonstrated efficacy in preclinical models of subarachnoid hemorrhage, renal fibrosis, and liver fibrosis.

Product Properties

• Molecular Weight: 572.62
• Purity: 99.33% (May vary between batches)
• CAS Number: [2828433-17-4]
• Formula: C23H43F3N6O7
• Target: TGF-beta/Smad

Application Notes

• Application Notes: Solubility: DMSO:200 mg/mL (349.27 mM),H2O:80 mg/mL (139.71 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.73 mM)