WAY-600, CAS [[1062159-35-6]]

Catalog Number: BYT-ORB1685620
Article Name: WAY-600, CAS [[1062159-35-6]]
Biozol Catalog Number: BYT-ORB1685620
Supplier Catalog Number: orb1685620
Alternative Catalog Number: BYT-ORB1685620-1, BYT-ORB1685620-1, BYT-ORB1685620-10, BYT-ORB1685620-100, BYT-ORB1685620-2, BYT-ORB1685620-25, BYT-ORB1685620-5, BYT-ORB1685620-50, BYT-ORB1685620-500
Manufacturer: Biorbyt
Category: Biochemikalien
Alternative Names: Mammalian target of Rapamycin, Inhibitor, mTOR, inhibit, Src, WAY 600, PI3Kgamma, PI3Kalpha, WAY600, WAY-600, VEGFR2
WAY-600 is a potent and selective ATP-competitive mTOR inhibitor with an IC50 of 9 nM. It effectively suppresses both mTORC1 and mTORC2 signaling by inhibiting phosphorylation of S6K(T389) and AKT(S473), respectively, and demonstrates high selectivity over PI3K isoforms. This inhibitor is a valuable tool for studying mTOR-dependent pathways in cancer and metabolic disease research, applicable in both cellular and in vivo models.
Molecular Weight: 494.59
Purity: 99.88% (May vary between batches)
CAS Number: [1062159-35-6]
Formula: C28H30N8O
Target: Src,mTOR,PI3K,VEGFR
Application Notes: Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.04 mM),Ethanol:2 mg/mL (4.04 mM),H2O:< 1 mg/mL (insoluble or slightly soluble),DMSO:45 mg/mL (90.98 mM)