TAME, CAS [[901-47-3]]

Product Overview

• Article Name: TAME, CAS [[901-47-3]]
• Biozol Catalog Number: BYT-ORB1685626
• Supplier Catalog Number: orb1685626
• Alternative Catalog Number: BYT-ORB1685626-1, BYT-ORB1685626-5
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Tosyl-Arginine Methyl Este, Tosylarginine methyl ester, TAME, APC, Anaphase promoting complex, N-4-Tosyl-L-arginine methyl ester

Product Description

TAME is a cell-permeable inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C). It functions by competitively blocking the binding of the activators Cdc20 and Cdh1, thereby inhibiting APC/C-dependent proteolysis. This compound is a valuable tool for studying cell cycle regulation, mitotic exit, and aneuploidy in both cellular and biochemical assays.

Product Properties

• Molecular Weight: 342.41
• CAS Number: [901-47-3]
• Formula: C14H22N4O4S
• Target: APC/C

Application Notes

• Application Notes: Solubility: Ethanol:3 mg/mL (8.76 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.64 mM),H2O:63 mg/mL (183.99 mM),DMSO:80 mg/mL (233.64 mM)