AKI603, CAS [[1432515-73-5]]

Product Overview

• Article Name: AKI603, CAS [[1432515-73-5]]
• Biozol Catalog Number: BYT-ORB1685708
• Supplier Catalog Number: orb1685708
• Alternative Catalog Number: BYT-ORB1685708-1, BYT-ORB1685708-1, BYT-ORB1685708-10, BYT-ORB1685708-100, BYT-ORB1685708-200, BYT-ORB1685708-25, BYT-ORB1685708-5, BYT-ORB1685708-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: imatinib-resistant, leukemia, Inhibitor, inhibit, myeloid, AKI 603, AKI603, AKI-603, Aurora A, AuroraKinase, Aurora Kinase, CML, chronic

Product Description

AKI603 is a potent and selective Aurora kinase A (AurA) inhibitor with an IC50 of 12.3 nM. It was developed to target BCR-ABL-T315I mutation-driven resistance, demonstrating robust anti-proliferative effects in leukemic cell lines in vitro and showing potential for leukemia research.

Product Properties

• Molecular Weight: 409.45
• Purity: 99.81% (May vary between batches)
• CAS Number: [1432515-73-5]
• Formula: C19H23N9O2
• Target: Aurora Kinase

Application Notes

• Application Notes: Solubility: DMSO:120 mg/mL (293.08 mM)