PG01, CAS [[853138-65-5]]

Product Overview

• Article Name: PG01, CAS [[853138-65-5]]
• Biozol Catalog Number: BYT-ORB1706800
• Supplier Catalog Number: orb1706800
• Alternative Catalog Number: BYT-ORB1706800-1, BYT-ORB1706800-1, BYT-ORB1706800-10, BYT-ORB1706800-100, BYT-ORB1706800-200, BYT-ORB1706800-25, BYT-ORB1706800-5, BYT-ORB1706800-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: CFTR, F508del-CFTR, PG01, PG-01, PG 01, Phenylglycine-01

Product Description

PG01 is a potent CFTR chloride channel potentiator effective against multiple CFTR mutants, including deltaF508, E193K, G970R, and G551D, with sub-micromolar affinity. It corrects gating defects by enhancing forskolin-stimulated chloride currents, making it a valuable research tool for in vitro cystic fibrosis studies and CFTR pharmacology investigations.

Product Properties

• Molecular Weight: 439.55
• Purity: 99.87% (May vary between batches)
• CAS Number: [853138-65-5]
• Formula: C28H29N3O2
• Target: CFTR

Application Notes

• Application Notes: Solubility: DMSO:30 mg/mL (68.25 mM)