AMG-009 is a potent small molecule dual antagonist targeting both the CRTH2 and DP receptors with high selectivity, exhibiting IC50 values of 3 nM and 12 nM, respectively. It is a valuable research tool for investigating the roles of these prostanoid receptors in allergic inflammation and asthma, applicable in both in vitro binding assays and in vivo disease models.
Molecular Weight:
581.47
Purity:
97.88% (May vary between batches)
CAS Number:
[1027847-67-1]
Formula:
C26H26Cl2N2O7S
Target:
GPCR,Prostaglandin Receptor
Application Notes:
Solubility: DMSO:100 mg/mL (171.98 mM)
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