6(5H)-Phenanthridinone is a dual PARP1/PARP2 inhibitor that suppresses radiation-induced proliferation in murine lymphoma cells and reduces pro-inflammatory cytokine expression in lymphocytes. In vivo, it ameliorates EAE in rats by decreasing spinal cord iNOS and cytokine levels, while also reducing hepatic oxidative damage and serum LDH.
Molecular Weight:
195.22
CAS Number:
[1015-89-0]
Formula:
C13H9NO
Target:
PARP,Others
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