PD-321852 is a selective Chk1 inhibitor that enhances gemcitabine cytotoxicity in pancreatic cancer models, as demonstrated by in vitro studies showing synergistic chemosensitization and loss of Chk1 protein. This compound is a valuable research tool for investigating DNA damage response pathways and combination chemotherapy strategies.
Molecular Weight:
468.33
CAS Number:
[622856-21-7]
Formula:
C24H19Cl2N3O3
Target:
Chk,Others
* VAT and and shipping costs not included. Errors and price changes excepted
