TM2 TEAD inhibitor, CAS [[1008768-41-9]]

Product Overview

• Article Name: TM2 TEAD inhibitor, CAS [[1008768-41-9]]
• Biozol Catalog Number: BYT-ORB1979922
• Supplier Catalog Number: orb1979922
• Alternative Catalog Number: BYT-ORB1979922-1, BYT-ORB1979922-10, BYT-ORB1979922-100, BYT-ORB1979922-25, BYT-ORB1979922-5, BYT-ORB1979922-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: TEAD-IN-8

Product Description

TM2 is a potent, reversible TEAD inhibitor that blocks auto-palmitoylation (IC50: 38 nM TEAD4) and disrupts TEAD-YAP transcriptional activity. It demonstrates significant antiproliferative effects in YAP-dependent cancer cells and potently inhibits the growth of YAP-driven liver organoids in vitro, supporting its investigation as an anticancer therapeutic.

Product Properties

• Molecular Weight: 435.57
• Purity: 99.91% (May vary between batches)
• CAS Number: [1008768-41-9]
• Formula: C26H33N3O3
• Target: YAP