PD-L1-IN-3, CAS [[2953044-29-4]]

Product Overview

• Article Name: PD-L1-IN-3, CAS [[2953044-29-4]]
• Biozol Catalog Number: BYT-ORB2278042
• Supplier Catalog Number: orb2278042
• Alternative Catalog Number: BYT-ORB2278042-1,BYT-ORB2278042-5,BYT-ORB2278042-10,BYT-ORB2278042-25,BYT-ORB2278042-50,BYT-ORB2278042-100
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 µM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma.

Product Properties

• Molecular Weight: 373.85
• Purity: 99.47%
• CAS Number: [2953044-29-4]
• Formula: C19H15ClFN2OS
• Target: PD-1/PD-L1