WRN inhibitor 15 (Compound 9) is a small molecule targeting the Werner syndrome helicase, exhibiting antitumor activity with IC50 values of 37.9-46.6 µM in prostate and cervical cancer cell lines. It is a useful chemical probe for in vitro studies of DNA damage response and synthetic lethality in microsatellite unstable cancers.
Molecular Weight:
301.29
Formula:
C16H13F2N3O
Target:
DNA/RNA Synthesis
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