IRF1-IN-1, CAS [[701225-07-2]]

Product Overview

• Article Name: IRF1-IN-1, CAS [[701225-07-2]]
• Biozol Catalog Number: BYT-ORB2814595
• Supplier Catalog Number: orb2814595
• Alternative Catalog Number: BYT-ORB2814595-1, BYT-ORB2814595-25, BYT-ORB2814595-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

IRF1-IN-1 is a small molecule inhibitor of IRF1 that blocks its recruitment to the Caspase 1 promoter, thereby suppressing the cleavage of downstream targets like GSDMD, IL-1beta, and PARP1. This mechanism has shown protective effects against skin inflammation in relevant research models, making it a useful tool for studying pyroptosis and inflammatory dermatoses in vitro and in vivo.

Product Properties

• Molecular Weight: 440.52
• Purity: 99.88% (May vary between batches)
• CAS Number: [701225-07-2]
• Formula: C22H24N4O4S
• Target: Interleukin,Pyroptosis,PARP,IFNAR,IL Receptor,Caspase

Application Notes

• Application Notes: Solubility: DMSO:80 mg/mL (181.6 mM),10% DMSO+40% PEG300+5% Tween-80+45% Saline:5 mg/mL (11.35 mM)