PKD2 (phospho Ser876) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: PKD2 (phospho Ser876) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES1432
• Supplier Catalog Number: ES1432
• Alternative Catalog Number: EBT-ES1432-50, EBT-ES1432-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human PKD2 around the phosphorylation site of Ser876. AA range:829-878
• Alternative Names: PRKD2, PKD2, HSPC187, Serine/threonine-protein kinase D2, nPKC-D2

Product Description

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 96kD
• NCBI: 25865
• UniProt: Q9BZL6

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Images

Western Blot analysis of various cells using Phospho-PKD2 (S876) Polyclonal Antibody diluted at 1:1000

Western Blot analysis of HELA cells using Phospho-PKD2 (S876) Polyclonal Antibody diluted at 1:1000

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using PKD2 (Phospho-Ser876) Antibody

Western blot analysis of lysates from NIH/3T3 cells treated with PMA 250ng/ml 15, using PKD2 (Phospho-Ser876) Antibody. The lane on the right is blocked with the phospho peptide.