IP3 Receptor Inhibitor 911 [Diphenyl (2,6-diaminohexanoate-O,N)-borane]

Catalog Number: ECH-B-0370
Article Name: IP3 Receptor Inhibitor 911 [Diphenyl (2,6-diaminohexanoate-O,N)-borane]
Biozol Catalog Number: ECH-B-0370
Supplier Catalog Number: B-0370
Alternative Catalog Number: ECH-B-0370-1MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
Diphenyl (2-6-diaminohexaonate-O,N)-borane is a more potent analog of 2-aminoethyldiphenyl borinate (2-APB), a known IP3 receptor inhibitor which can regulate IP3-induced calcium release. Diphenyl (2,6-diaminohexaonate-O, N)-borane (compound 911 in Ozaki et al.) has an IC50 = 0.2mM as measured by Store-Operated Calcium Entry (SOCE) and IP3 Induced Calcium Release (IICR) assays.

Storage

4 C or below

References

S. Ozaki, P.O. Bauer, et al. ''2-Aminoethyl diphenylborinate (2-APB) analogues: Regulators of Ca2+ release and consequent cellular processes Biochem. Biophys. Res. Commun., 441, 2013, 286-290.

Documents

Technical Data Sheet
Application Notes: Categories: Biochemical Reagents. Related: Inhibitor. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature