Very potent protein kinase C (PKC) inhibitor with high selectivity for the PKC isotypes alpha and beta. Inhibits PKCalpha (IC50=2.3nM) and PKCß1 (IC50=6.2nM) but has no effect on delta, epsilon or gamma isotypes. Potent antagonist of HIV-1 induction.
Molecular Weight:
378.4
Purity:
95% (HPLC, TLC)
CAS Number:
[136194-77-9]
Formula:
C24H18N4O
Target:
PKC alpha, PKC beta I
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