SP-600125, CAS [[129-56-6]]

Product Overview

• Article Name: SP-600125, CAS [[129-56-6]]
• Biozol Catalog Number: FBM-10-1033
• Supplier Catalog Number: 10-1033
• Alternative Catalog Number: FBM-10-1033-10MG, FBM-10-1033-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Anthra[1-9-cd]pyrazol-6(2H)-one. Alternate Names: 1,9-Pyrazoloanthrone

Product Description

JNK inhibitor

Product Properties

• Molecular Weight: 220.23
• Purity: 98% by TLC NMR conforms
• Form: Yellow solid
• CAS Number: [129-56-6]
• Formula: C14H8N2O

Application Notes

• Application Notes: Selective inhibitor of c-Jun N-terminal kinase (JNK). Reversibly inhibits JNK1,2 and 3 (IC50s range from 40-90 nM). >300-fold selectivity for JNK as compared to related MAP kinases. Antiinflammatory activity. Inhibits expression of presenilin-1 and Notch signaling in mouse brain. Cell permeable and active in vivo.