STO-609, CAS [[52029-86-4]]

Product Overview

• Article Name: STO-609, CAS [[52029-86-4]]
• Biozol Catalog Number: FBM-10-1036
• Supplier Catalog Number: 10-1036
• Alternative Catalog Number: FBM-10-1036-5MG, FBM-10-1036-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid acetate

Product Description

CAMKK inhibitor

Product Properties

• Molecular Weight: 314.30 60.05
• Purity: 98% by TLC NMR conforms
• Form: Yellow solid
• CAS Number: [52029-86-4]
• Formula: C19H10N2O3 CH3COOH

Application Notes

• Application Notes: Selective inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki = 80 and 15 ng/ml for inhibition of CaM-KKalpha and CaM-KKbeta respectively).1 Binds to the ATP-binding site.2 Displays > 80-fold selectivity over CaMK1, CaMK2, CaMK4, MLCK, PKC, PKA and p42 MAPK. Important tool for probing distinct CaMK pathways in LTP.3 Reduces starvation-induced autophagosomal membrane formation.4 Reverses age-associated decline in bone mass.5 Stimulates osteoblast formation, inhibits osteoclast differentiation.6