Sunitinib malate, CAS [[341031-54-7]]

Catalog Number: FBM-10-1078
Article Name: Sunitinib malate, CAS [[341031-54-7]]
Biozol Catalog Number: FBM-10-1078
Supplier Catalog Number: 10-1078
Alternative Catalog Number: FBM-10-1078-10MG, FBM-10-1078-50MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimehyl-1H-pyrrole-3-carboxamide malate. Alternate Names: SU-11248
VEGFR, PDGFR kinase inhibitor
Molecular Weight: 532.57
Purity: 98% by TLC, NMR (Conforms)
Form: Orange solid
CAS Number: [341031-54-7]
Formula: C22H27FN4O4 C4H6O5
Application Notes: A potent inhibitor of multiple receptor tyrosine kinases including VEGFR, PDGFRbeta and Kit (Ki = 2-17 nM)1. Also inhibits cFMS (IC50=7 nM)2 and FLT33. Potent inhibitor of angiogenesis4. Clinically useful anticancer agent. Cell permeable.