Sivelestat, CAS [[127373-66-4]]

Product Overview

• Article Name: Sivelestat, CAS [[127373-66-4]]
• Biozol Catalog Number: FBM-10-1102
• Supplier Catalog Number: 10-1102
• Alternative Catalog Number: FBM-10-1102-5MG, FBM-10-1102-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium. Alternate Names: ONO-5046

Product Description

Leukocyte elastase inhibitor

Product Properties

• Molecular Weight: 456.45
• Purity: 98% by TLC
• Form: White solid
• CAS Number: [127373-66-4]
• Formula: C20H21N2O7

Application Notes

• Application Notes: Potent and selective leukocyte elastase inhibitor, IC50 = 44 nM1. Displays no activity at a variety of other proteases. Inhibits NF-kappaB activation2 and LTB4-induced neutrophil migration in vitro3. Significantly attenuates ischemia-induced spinal cord injury, decreases serum cytokine levels and reduces acute inflammatory lung injury in vivo4.