Vinpocetine, CAS [[42971-09-5]]

Product Overview

• Article Name: Vinpocetine, CAS [[42971-09-5]]
• Biozol Catalog Number: FBM-10-1126
• Supplier Catalog Number: 10-1126
• Alternative Catalog Number: FBM-10-1126-50MG,FBM-10-1126-250MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

PDE1 inhibitor

Product Properties

• Molecular Weight: 350.45
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [42971-09-5]
• Formula: C22H26N2O2

Application Notes

• Application Notes: Phosphodiesterase PDE1 inhibitor (IC50=21 µM)1. Also blocks voltage-gated Na+ channels, IC50=44.2 µM (potency similar to phenytoin), a mechanism which may contribute to its neuroprotective and anticonvulsant activity2. It reduces inflammatory IL-1beta and TNF-alpha expression in rat hippocampus3. Displays beneficial effects in a rat model of cerebral ischemia-reperfusion injury4. Exerts neuroprotective effects by suppressing microglial inflammation5.