Antazoline HCl, CAS [[2508-72-7]]

Product Overview

• Article Name: Antazoline HCl, CAS [[2508-72-7]]
• Biozol Catalog Number: FBM-10-1144
• Supplier Catalog Number: 10-1144
• Alternative Catalog Number: FBM-10-1144-500MG, FBM-10-1144-2G
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-(N-Benzylanilinomethyl)-2-imidazoline hydrochloride

Product Description

Antihistamine and neuroprotective

Product Properties

• Molecular Weight: 301.82
• Purity: >98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [2508-72-7]
• Formula: C17H19N3 HCl

Application Notes

• Application Notes: Antazoline (2508-72-7) displays neuroprotective effects against hypoxia-induced death in neuronal cultures, the mechanism of action being inhibition of NMDA currents (IC50=4 µM).1 It induces concentration-dependent stimulation of insulin secretion in rat pancreas which is mediated via imidazoline I1 receptors.2 It also acts as a histamine H1 receptor antagonist (Ki=38.4 nM, human recombinant H1 receptor)3 and was found to be a highly effective antiarrhythmic agent4.