Stavudine, CAS [[3056-17-5]]

Product Overview

• Article Name: Stavudine, CAS [[3056-17-5]]
• Biozol Catalog Number: FBM-10-1266
• Supplier Catalog Number: 10-1266
• Alternative Catalog Number: FBM-10-1266-200MG, FBM-10-1266-1G
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2,3-Didehydro-3-deoxythymidine. Alternate Names: BMY 27857, d4T

Product Description

HIV reverse transcriptase inhibitor

Product Properties

• Molecular Weight: 224.22
• Purity: >98% by HPLC, NMR (conforms)
• Form: White solid
• CAS Number: [3056-17-5]
• Formula: C10H12N2O4

Application Notes

• Application Notes: Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs).1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates Abeta-induced autophagy in macrophages.4