Trifluorothymidine, CAS [[70-00-8]]

Product Overview

• Article Name: Trifluorothymidine, CAS [[70-00-8]]
• Biozol Catalog Number: FBM-10-1283
• Supplier Catalog Number: 10-1283
• Alternative Catalog Number: FBM-10-1283-50MG,FBM-10-1283-250MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: alpha,alpha,alpha-Trifluorothymidine, Trifluorothymine deoxyriboside, Trifluridine, TFT

Product Description

Thymidylate synthase inhibitor, Anti-cancer agent

Product Properties

• Molecular Weight: 296.20
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [70-00-8]
• Formula: C10H11F3N2O5

Application Notes

• Application Notes: An analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes.3 Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.4