E-64d, CAS [[88321-09-9]]

Product Overview

• Article Name: E-64d, CAS [[88321-09-9]]
• Biozol Catalog Number: FBM-10-1347
• Supplier Catalog Number: 10-1347
• Alternative Catalog Number: FBM-10-1347-1MG, FBM-10-1347-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2S,3S-trans-(Ethoxycarbonyloxirane-2-carbonyl)-L-leucine-(3-methylbutyl)amide. Alternate Names: Aloxistatin, Loxistatin

Product Description

Cysteine protease inhibitor

Product Properties

• Molecular Weight: 342.43
• Purity: 98% by HPLC NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [88321-09-9]
• Formula: C17H30N2O5

Application Notes

• Application Notes: Cell-permeable derivative of E-64c, an inhibitor of calpain and other cysteine proteases, such as papain, cathepsin B and cathepsin L.1,2 Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the ethyl ester and reduce cell permeability. Typical working concentration is 0.5-10 µg/ml. Inhibits degradation of autophagic cargo inside autolysosomes3