Daminozide, CAS [[1596-84-5]]

Product Overview

• Article Name: Daminozide, CAS [[1596-84-5]]
• Biozol Catalog Number: FBM-10-1403
• Supplier Catalog Number: 10-1403
• Alternative Catalog Number: FBM-10-1403-50MG, FBM-10-1403-250MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-(2,2-Dimethylhydrazide)butanedioic acid. Alternate Names: N-(Dimethylamino)succinamic acid

Product Description

KDM2/7 demethylase inhibitor

Product Properties

• Molecular Weight: 160.17
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [1596-84-5]
• Formula: C6H12N2O3

Application Notes

• Application Notes: A selective inhibitor of the KDM2/7 JmjC subfamily of histone demethylases. IC50=1.5, 0.55 and 2.1 µM for KDM2A, PHF8 and KDM7A respectively. Highly selective over other subfamily members (KDM3, KDM4, KDM5 and KDM6) as well as other 2-oxoglutarate oxygenases (FIH, PHD2 and BBOX1), IC50>100 µM1.