TG 4-155, CAS [[1164462-05-8]]

Product Overview

• Article Name: TG 4-155, CAS [[1164462-05-8]]
• Biozol Catalog Number: FBM-10-1574
• Supplier Catalog Number: 10-1574
• Alternative Catalog Number: FBM-10-1574-5MG, FBM-10-1574-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (2E)-N-[2-(2-Methyl-1H-indol-1-yl)ethyl]-3-(3,4,5-trimethoxyphenyl)-2-propenamide

Product Description

EP2 receptor antagonist

Product Properties

• Molecular Weight: 394.47
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1164462-05-8]
• Formula: C23H26N2O4

Application Notes

• Application Notes: Potent and selective prostaglandin EP2 receptor antagonist, KB = 2.4 and 34.5 nM for EP2 and DP1 receptors respectively. Displays >500-fold selectivity for EP2 over other prostanoid receptors.1 Inhibits butaprost-induced proinflammatory cytokine production, cell proliferation and invasion of PC-3 cells in vitro.2 Inhibits PGE2-induced inflammatory response and may represent a novel pharmacologic intervention for tumorigenesis resulting from inflammation.1