Meleagrin, CAS [[71751-77-4]]

Product Overview

• Article Name: Meleagrin, CAS [[71751-77-4]]
• Biozol Catalog Number: FBM-10-1599
• Supplier Catalog Number: 10-1599
• Alternative Catalog Number: FBM-10-1599-1MG, FBM-10-1599-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (3E,7aR,12aS-7a-(1,1-Dimethyl-2-propen-1-yl)-7a,12-dihydro-6-hydroxy-3-(1H-imidazol-5-ylmethylene)-12-methoxy-1H,5H-imidazol[1,2:1,2]pyrido[2,3-b]indole-2,5(3H)-dione

Product Description

Met inhibitor, Anticancer activity

Product Properties

• Molecular Weight: 433.46
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Tan lyophilized solid
• CAS Number: [71751-77-4]
• Formula: C23H23N5O4

Application Notes

• Application Notes: A novel alkaloid biosynthesized via the roquefortine branched biosynthetic pathway.1,2 Displays excellent ATP-competitive c-MET inhibition, inhibiting the growth, migration and invasion of numerous breast cancer cell lines.3 Also has been shown to inhibit the bacterial enoyl-acyl carrier protein reductase (Fabl) with IC50s in the 33-40 µM range.4