Entacapone, CAS [[130929-57-6]]

Product Overview

• Article Name: Entacapone, CAS [[130929-57-6]]
• Biozol Catalog Number: FBM-10-2025
• Supplier Catalog Number: 10-2025
• Alternative Catalog Number: FBM-10-2025-10MG, FBM-10-2025-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide

Product Description

COMT inhibitor - anti-Parkinsons

Product Properties

• Molecular Weight: 305.29
• Purity: 98% by HPLC, NMR (Conforms)
• Form: Yellow solid
• CAS Number: [130929-57-6]
• Formula: C14H15N3O5

Application Notes

• Application Notes: Potent catechol O-methyltransferase (COMT) inhibitor (IC50 = 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT respectively).1 Increases bioavailability of L-DOPA as adjunct therapy for Parkinsons disease.2 Inhibits alpha-synuclein aggregation in vitro and inhibits alpha-synuclein-induced cell death in PC-12 cells3. Antioxidant. Inhibits oxidative stress-induced cell death4.