Cytochalasin B, CAS [[14930-96-2]]

Product Overview

• Article Name: Cytochalasin B, CAS [[14930-96-2]]
• Biozol Catalog Number: FBM-10-2069
• Supplier Catalog Number: 10-2069
• Alternative Catalog Number: FBM-10-2069-1MG, FBM-10-2069-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Fermentation product from Drechslera dematioidea. Alternate Names: NSC107658, Phominone, Phomin

Product Description

Actin filament disrupting agent

Product Properties

• Molecular Weight: 479.61
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [14930-96-2]
• Formula: C29H37NO5

Application Notes

• Application Notes: A cell permeable fungal toxin which binds to the barbed end of actin, inhibiting its polymerization.1 Inhibits cell division, migration and glucose transport.2 Causes cell cycle arrest at G2/M and induces apoptosis in HCT-116 colorectal carcinoma cells.3 Cytochalasin B-induced membrane vesicles (CIMVs) retain cell surface receptors of the parent cells and retain fusion specificity with target cells.4 CIMVs are a promising new vector system for drug and biomolecule delivery due to their natural origin and participation in intercellular communication.5