Thiostrepton, CAS [[1393-48-2]]

Product Overview

• Article Name: Thiostrepton, CAS [[1393-48-2]]
• Biozol Catalog Number: FBM-10-2108
• Supplier Catalog Number: 10-2108
• Alternative Catalog Number: FBM-10-2108-1G, FBM-10-2108-5G
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: Fermentation product from Streptomyces azureus

Product Description

Antibiotic and FOXM1 inhibitor

Product Properties

• Molecular Weight: 1664.91
• Purity: 98% by TLC and HPLC
• Form: Off-white solid
• CAS Number: [1393-48-2]
• Formula: C72H85N19O18S5

Application Notes

• Application Notes: Novel cyclopeptide antibiotic. Blocks bacterial protein synthesis by inhibition of mRNA-tRNA translocation by GTPase elongation factor G (EF-G), EF-TU(GTP)-catalyzed aa-tRNA delivery as well as the activity of initiation factor-1 (IF-2)1-2. Displays antitumor activity. Induces apoptosis and cell cycle arrest in various tumor cells via downregulation of FOXM1 expression3.