Leflunomide, CAS [[75706-12-6]]

Product Overview

• Article Name: Leflunomide, CAS [[75706-12-6]]
• Biozol Catalog Number: FBM-10-2369
• Supplier Catalog Number: 10-2369
• Alternative Catalog Number: FBM-10-2369-50MG, FBM-10-2369-250MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-Methyl-N-[4-(trifluoromethyl)phenyl]-4-isoxazolecarboxamide. Alternate Names: RS-34821

Product Description

Immunosuppressant

Product Properties

• Molecular Weight: 270.21
• Purity: 98% by TLC, NMR (conforms)
• Form: White solid
• CAS Number: [75706-12-6]
• Formula: C12H9F3N2O2

Application Notes

• Application Notes: A pyrimidine biosynthesis inhibitor DMARD (disease-modifying antirheumatic drug)1. Displays immunomodulatory activity inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH)2. Although the molecule directly responsible for DHODH is actually A77 1726, a metabolite of Leflunomide. Rescues mice from acetaminophen-induced liver injury3.