SB-3CT, CAS [[292605-14-2]]

Product Overview

• Article Name: SB-3CT, CAS [[292605-14-2]]
• Biozol Catalog Number: FBM-10-2493
• Supplier Catalog Number: 10-2493
• Alternative Catalog Number: FBM-10-2493-5MG, FBM-10-2493-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-[[(4-Phenoxyphenyl)sulfonyl]methyl]-thiirane

Product Description

MMP-2 inhibitor

Product Properties

• Molecular Weight: 306.39
• Purity: >98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [292605-14-2]
• Formula: C15H14O3S2

Application Notes

• Application Notes: SB-3CT (292605-14-2) is a potent and selective inhibitor of MMP2 (Ki=28 nm) which also inhibits MMP9 (Ki=400 nM).1 The drug rescues laminin from proteolysis and neurons from apoptosis in a transient focal cerebral ischemia mouse model.2 It abrogates elevation of blood brain barrier (BBB) permeability in mouse Parkinsons disease models3 and improves specific neurobehavioral deficits in a mouse model of Alzheimers disease4. BBB permeable.