Damnacanthal, CAS [[477-84-9]]

Product Overview

• Article Name: Damnacanthal, CAS [[477-84-9]]
• Biozol Catalog Number: FBM-10-2516
• Supplier Catalog Number: 10-2516
• Alternative Catalog Number: FBM-10-2516-1MG, FBM-10-2516-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 9,10-Dihydroxy-3-hydroxy-1-methoxy-9,10-dioxo-2-anthracenecarboxaldehyde

Product Description

p56 Lck inhibitor

Product Properties

• Molecular Weight: 282.25
• Purity: 98% by TLC, NMr (Conforms)
• Form: Yellow solid
• CAS Number: [477-84-9]
• Formula: C16H10O5

Application Notes

• Application Notes: Potent inhibitor of p56lck tyrosine kinase activity (IC50 = 17 nM for inhibition of autophosphorylation). Displays 7- to 20-fold selectivity over p59fyn and p60src tyrosine kinases and > 40-fold to 100-fold selectivity over other kinases1. Mobilizes intracellular Ca2+ in dermal fibroblasts2. Inhibits LIM-kinase, impairing cell migration and invasion3. A potent inhibitor of angiogenesis4. Inhibits mast cell activation5.