Tenovin-1, CAS [[380315-80-0]]

Product Overview

• Article Name: Tenovin-1, CAS [[380315-80-0]]
• Biozol Catalog Number: FBM-10-2982
• Supplier Catalog Number: 10-2982
• Alternative Catalog Number: FBM-10-2982-5MG, FBM-10-2982-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-[(4-Acetamidophenyl)carbamothioyl]-4-tert-butylbenzamide

Product Description

SIRT1 and 2 inhibitor

Product Properties

• Molecular Weight: 369.48
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [380315-80-0]
• Formula: C20H23N3O2S

Application Notes

• Application Notes: Tenovin-1 activates p53 via inhibition of SIRT1 and SIRT2.1,2 Induces apoptosis in a variety of cancer cell lines including cutaneous T-cell lymphoma3 and melanoma4 among others5. Induces cellular senescence in cultured rat primary astrocytes6 as well as other cell types.