Teleocidin A1, CAS [[70497-14-2]]

Catalog Number: FBM-10-3339
Article Name: Teleocidin A1, CAS [[70497-14-2]]
Biozol Catalog Number: FBM-10-3339
Supplier Catalog Number: 10-3339
Alternative Catalog Number: FBM-10-3339-200UG, FBM-10-3339-1MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: (10S,13S)-5-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-13-(hydroxymethyl)-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4,6,8(15)-tetraen-11-one. Alternate Names: Lyngbyatoxin A
Non-phorbol ester PKC activator
Molecular Weight: 437.63
Purity: >95% by HPLC, NMR (Conforms)
Form: White solid/wax
CAS Number: [70497-14-2]
Formula: C27H39N3O2
Application Notes: Teleocidin A1 is a selective protein kinase C activator1 (EC50 = 40 ng/ml) representing a new class of non-phorbol ester tumor promotor2. Teleocidin A1 mimics the effect of diacylglycerol (DAG), activating PKC, but unlike DAG causes persistent activation.3 It enhances actin redistribution, vacuole formation and c-fos expression in PLC/PRF/5 hepatoma cells.4 Occurs in toxic cyanobacterial blooms.5