TH301, CAS [[450338-32-6]]

Product Overview

• Article Name: TH301, CAS [[450338-32-6]]
• Biozol Catalog Number: FBM-10-3909
• Supplier Catalog Number: 10-3909
• Alternative Catalog Number: FBM-10-3909-5MG, FBM-10-3909-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-(4-Chlorophenyl)-N-[2,6-dihydro-2-(4-methoxyphenyl)-5,5-dioxido-4H-thieno[3,4-c]pyrazol-3-yl]cyclopentanecarboxamide

Product Description

Selective circadian clock protein CRY2 stabilizer

Product Properties

• Molecular Weight: 485.98
• Purity: 98% by HPLC NMR (conforms)
• Form: White solid
• CAS Number: [450338-32-6]
• Formula: C24H24ClN3O4S

Application Notes

• Application Notes: TH301 is an isoform-selective stabilizer of the circadian clock protein CRY2. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. TH301 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.