SB-705498, CAS [[501951-42-4]]

Product Overview

• Article Name: SB-705498, CAS [[501951-42-4]]
• Biozol Catalog Number: FBM-10-3985
• Supplier Catalog Number: 10-3985
• Alternative Catalog Number: FBM-10-3985-5MG, FBM-10-3985-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-(2-Bromophenyl)-3-[(3R)-1-[5-(trifluoromethyl)pyridine-2-yl]pyrrolidine-3-yl]urea

Product Description

TRPV1 antagonist

Product Properties

• Molecular Weight: 429.24
• Purity: 98% by HPLC , NMR (Conforms)
• Form: White solid
• CAS Number: [501951-42-4]
• Formula: C17H16BrF3N4O

Application Notes

• Application Notes: Potent and selective antagonist of the TRPV1 receptor (IC50s for receptor induction method: Capsaicin = 3 nM, Acid (pH5.3) = pIC50 7.1, and Heat = 6 nM) with activity in human, rat, and guinea pig receptors.1,2 SB-705498s activity is voltage dependent and shows >100 fold selectivity over the closely related TRPM8 receptor.2