SP2509, CAS [[1423715-09-6]]

Product Overview

• Article Name: SP2509, CAS [[1423715-09-6]]
• Biozol Catalog Number: FBM-10-4019
• Supplier Catalog Number: 10-4019
• Alternative Catalog Number: FBM-10-4019-5MG, FBM-10-4019-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (E)-N-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-(morpholinosulfonyl)benzohydrazide. Alternate Names: HCI-2509

Product Description

LSD1 inhibitor

Product Properties

• Molecular Weight: 437.90
• Purity: 98% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [1423715-09-6]
• Formula: C19H20ClN3O5S

Application Notes

• Application Notes: Potent (IC50 = 13 nM) and reversible inhibitor of the histone demethylase LSD1 (KDM1A).1 It is inactive against the closely related flavin enzymes MAO A,B as well as lactate dehydrogenase, several CYPs and hERG. LSD1 regulates the balance between self-renewal and differentiation of stem cells and is highly expressed in various cancers.2-6 SP2509 promotes autophagy in neuroblastoma cells.7