Chemical Name: 2,3-Dihydroxypropyl 2-(3-chloro-2-methylanilino)pyridine-3-carboxylate. Alternate Names: CXL
STING antagonist
Molecular Weight:
336.77
Purity:
>98% by HPLC NMR (Conforms)
Form:
Pale yellow solid
CAS Number:
[21829-22-1]
Formula:
C16H17ClN2O4
Application Notes:
Clonixeril is an ultra-potent antagonist of human STING. It acts as a STING agonist at micromolar concentrations but is an antagonist in the 1 nM to 100 aM range in THP-1 cells. Its antagonistic behavior occurs via modulation of STING oligomerization.
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