LDC1267, CAS [[1361030-48-9]]

Product Overview

• Article Name: LDC1267, CAS [[1361030-48-9]]
• Biozol Catalog Number: FBM-10-4420
• Supplier Catalog Number: 10-4420
• Alternative Catalog Number: FBM-10-4420-5MG, FBM-10-4420-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluoro-2-methylphenyl)-1H-pyrazole-3-carboxamide

Product Description

Selective inhibitor of TAM kinases

Product Properties

• Molecular Weight: 560.56
• Purity: >98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [1361030-48-9]
• Formula: C30H26F2N4O5

Application Notes

• Application Notes: LDC1267 is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.