Autogramin-2, CAS [[2375541-45-8]]

Product Overview

• Article Name: Autogramin-2, CAS [[2375541-45-8]]
• Biozol Catalog Number: FBM-10-4439
• Supplier Catalog Number: 10-4439
• Alternative Catalog Number: FBM-10-4439-5MG, FBM-10-4439-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: t-Butyl 2-[(4-propan-2-yloxybenzoyl)amino]-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate

Product Description

Autophagy blocker GRAMD1A inhibition

Product Properties

• Molecular Weight: 417.53
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [2375541-45-8]
• Formula: C21H27N3O4S

Application Notes

• Application Notes: Autogramin-2 is an inhibitor of autophagy (autophagy induced by amino acid starvation IC50 = 270 nM, Rapamycin IC50 = 140 nM) acting via selective targeting of the cholesterol transfer protein GRAM domain-containing protein 1A (GRAMD1A). Autogramin-2 inhibition of GRAMD1A inhibits biogenesis of the autophagosome.