Afatinib, CAS [[850140-72-6]]

Product Overview

• Article Name: Afatinib, CAS [[850140-72-6]]
• Biozol Catalog Number: FBM-10-4510
• Supplier Catalog Number: 10-4510
• Alternative Catalog Number: FBM-10-4510-10MG, FBM-10-4510-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide. Alternate Names: BIBW2992

Product Description

EGFR and HER2 inhibitor

Product Properties

• Molecular Weight: 485.94
• Purity: 99% by HPLC, NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [850140-72-6]
• Formula: C24H25ClFN5O3

Application Notes

• Application Notes: Afatinib is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50 = 0.5 nM) and HER2 (IC50 = 14 nM).