GW1100, CAS [[306974-70-9]]

Product Overview

• Article Name: GW1100, CAS [[306974-70-9]]
• Biozol Catalog Number: FBM-10-4516
• Supplier Catalog Number: 10-4516
• Alternative Catalog Number: FBM-10-4516-5MG, FBM-10-4516-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-(4-Ethoxycarbonylphenyl-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone

Product Description

GPR40 antagonist

Product Properties

• Molecular Weight: 520.59
• Purity: 96% by LCMS NMR (Conforms)
• Form: White solid
• CAS Number: [306974-70-9]
• Formula: C27H25FN4O4S

Application Notes

• Application Notes: Selective antagonist of GPR40. GW1100 inhibits GRP40-mediated Ca2+ increases stimulated GW9508 or linoleic acid (pIC50 = 5.99 for either agonist).1 The effects of GPR40 activation on insulin secretion in cells are also blocked by the addition of GW1100. GW1100 does not influence calcium mobilization mediated by GPR120.