BML283, CAS [[562867-96-3]]

Product Overview

• Article Name: BML283, CAS [[562867-96-3]]
• Biozol Catalog Number: FBM-10-4561
• Supplier Catalog Number: 10-4561
• Alternative Catalog Number: FBM-10-4561-5MG, FBM-10-4561-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-ylsulfonyl)-4-(4-methoxyphenylsulfonyl)piperazine. Alternate Names: ML083

Product Description

PKM2 activator

Product Properties

• Molecular Weight: 454.51
• Purity: 98% by TLC, NMR (Conforms)
• Form: white solid
• CAS Number: [562867-96-3]
• Formula: C19H22N2O7S2

Application Notes

• Application Notes: BML283 is a selective activator of the Tumor Specific M2 Isoform of Pyruvate Kinase (PKM2) - AC50 = 111nM.1 PKM2 activity is downregulated in most cancer cells leading to a decrease in catabolic metabolism and an increase in anabolic metabolism.2,3 BML283 is an important tool for studying the effects of PKM2 and cancer metabolism.