Rbin-1, CAS [[328023-11-6]]

Product Overview

• Article Name: Rbin-1, CAS [[328023-11-6]]
• Biozol Catalog Number: FBM-10-4606
• Supplier Catalog Number: 10-4606
• Alternative Catalog Number: FBM-10-4606-5MG, FBM-10-4606-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-[(2-Methyl-2-propen-1-yl)sulfanyl]-5H-[1,2,4]triazino[5,6-b]indole

Product Description

Eukaryotic ribosome assembly inhibitor

Product Properties

• Molecular Weight: 256.33
• Purity: >98% by TLC, NMR (Conforms)
• Form: Pale yellow solid
• CAS Number: [328023-11-6]
• Formula: C13H12N4S

Application Notes

• Application Notes: Rbin-1 is potent (GI50 = 136 nM) and reversible inhibitor of eukaryotic ribosome assembly. The biochemical target of Rbin-1 is Midasin (Mdn1), an essential AAA+ protein. Blocking of Mdn1 by Rbin-1 inhibits the processing of pre-60S particles, important pre-ribosomal subunits produced in the nucleolus.