Linsitinib, CAS [[867160-71-2]]

Product Overview

• Article Name: Linsitinib, CAS [[867160-71-2]]
• Biozol Catalog Number: FBM-10-4814
• Supplier Catalog Number: 10-4814
• Alternative Catalog Number: FBM-10-4814-10MG, FBM-10-4814-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-[8-Amino-1-(2-phenyl-7-quinolyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol. Alternate Names: OSI-906

Product Description

IGF-1R kinase / InsR kinase inhibitor

Product Properties

• Molecular Weight: 421.49
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [867160-71-2]
• Formula: C26H23N5O

Application Notes

• Application Notes: Linsitinib is a potent and selective dual inhibitor of insulin-like growth factor 1 (IGF-1R) kinase and insulin receptor (InsR) kinase (IC50s = 35 and 75 nM respectively).1 It has been investigated as a chemotherapeutic in combination with other drugs for various cancers.2-6