STC-15, CAS [[2648257-56-9]]

Catalog Number: FBM-10-4874
Article Name: STC-15, CAS [[2648257-56-9]]
Biozol Catalog Number: FBM-10-4874
Supplier Catalog Number: 10-4874
Alternative Catalog Number: FBM-10-4874-5MG, FBM-10-4874-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: N-[[2-[(Cyclobutylmethylamino)methyl]-1H-indol-6-yl]methyl]-4-oxopyrido[1,2-a]pyrimidine-2-carboxamide
METTL3 inhibitor
Molecular Weight: 415.50
Purity: >98% by HPLC NMR (Conforms)
Form: Pale yellow solid
CAS Number: [2648257-56-9]
Formula: C24H25N5O2
Application Notes: STC-15 is an orally bioavailable inhibitor of the RNA methyltransferase METTL3. Inhibits acute myeloid leukemia growth and induces anti-cancer immunity via activation of double strand RNA sensing machinery and interferon signaling. STC-15 synergizes with radiation therapy and T cell checkpoint blockade and enhances the cytotoxicity of doxorubicin chemotherapy.