Chemical Name: N-(5-Bromo-3-chloro-2-hydroxyphenyl)-2-(11-oxo-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetamide
YTHDC2 inhibitor
Molecular Weight:
472.72
Purity:
>98% by TLC NMR (Conforms)
Form:
Pale pink solid
Formula:
C22H15BrClNO4
Application Notes:
DC2-C1 is a potent (IC50 = 168 nM) inhibitor of the RNA N6-methyladenosine reader YTHDC2. YTHDC2 can act as both a tumor suppressor and oncogene as well as being involved in metabolic regulation. DC2-C1 is selective for YTHDC2 over other YTH-domain proteins. Cell permeable.
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